International Journal of Applied Microbiology and Biotechnology Research
ISSN: 2053-1818
Vol. 7(4), pp. 46-54, May, 2019

Effectiveness of traditional medicinal herbs against pathogens causing wide spread diseases

Fahim Ullah, Safina Sharif, Muhammad Zakir, Mohammad Iqbal Khan and Murad Ali Khan*

Department of Chemistry, Kohat University of Science and Technology, Kohat, Pakistan.

*To whom correspondence should be addressed. E-mail:

Received 21 February, 2019; Received in revised form 14 May, 2019; Accepted 16 May, 2019.


Foeniculum vulgare, Curcuma longa, Berberis vulgaris, Bacterial strains, Fungal strains.

The complications due to microbes are in the rise in developing countries especially in the remote areas due to non-availability of proper treatment. In this regards, people are compelled to use traditional herbs for treatments. In the present work the antimicrobial activity of three medicinal herbs, Foeniculum vulgare, Curcuma longa and Berberis vulgaris were studied for the actions against wide spread Gram-negative bacterial and fungal strains, Escherichia coli, Salmonella typhi, Mycoplasma gallisepticum and Shigella dysenteriae and four fungal strains, Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger and Fusarium solani by agar well diffusion method. The study shows that n-hexane and chloroform extracts of F. vulgare exhibited significant antibacterial activity against S. dysenteriae and M. gallisepticum while the crude and n-hexane fractions of C. longa exhibited promising antibacterial affect against E. coli and S. typhi, respectively. Ethyl acetate fraction of Berberis vulgaris showed good activity against M. gallisepticum, whereas Ethyl acetate fraction of C. longa showed the best activity against Aspergillus fumigates and A. niger. The study confirms the effectiveness of these medicinal plants and its different extract against the common diseases caused by E. coli, S. typhi, M. gallisepticum, S. dysenteriae, A. flavus, A. fumigatus, A. niger and F. solani.

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