International Journal of Research in Environmental Studies
ISSN: 2059-1977
Vol. 3(3), pp. 101-108, June 2016



Blood oxidant stress in relation to seasonal activity of thyroid and adrenal glands in Camelus dromedarius

JLEKTIB Islah1, BARGAÂ Rita2, FARH Mohamed2, EL ABBADI Najia3, TAHRI El hassane2, RIAD fouad2, BELHOUARI Abderrahmane2, HAMMOUMI Abderrahman1, EL MZIBRI Mohammed3 and EL KHASMI Mohammed2*

1Laboratory of Microbiology, Pharmacology, Biotechnology and Environment, Faculy of Sciences, Aïn-Chock, Hassan II University of Casablanca, P. B. 5366 Maârif, Casablanca, Morocco.
2Laboratory of Physiopathology and Molecular Genetic, Faculty of Sciences, Ben M’Sik, Hassan II University of Casablanca, P. B. 7955 Sidi Othmane, Casablanca, Morocco.
3Unit Radio-Immuno-Analysis/Division of Life Sciences, CNESTEN, B. P. 1382 RP 10001, Rabat, Morocco.

*To whom correspondence should be addressed. E-mail: elkhasmimohammed@gmail.com.

Received 317 March, 2016; Received in revised form 2 May, 2016; Accepted 6 May, 2016.

Abstract


Keywords:
Camel, Catalase, Cortisol, Malondialdehyde, Oxidant stress, Thyroid hormones.


It is a well-established fact that thyroid and adrenal gland activities show seasonal variations that are considered crucial to sustain the productive performance in domestic animals. Thyroid hormones (TH) and cortisol (COR) are physiologic modulators of tissue oxidation by regulating the expression of enzymes involved in all steps of oxidative stress (OS). The study was carried out to investigate the effects of seasonal variations on serum concentrations of total thyroxine (T4), total triiodothyronine (T3), COR, malondialdehyde (MDA) and catalase activity (CAT); and their correlations together in dromedarian camels (Camelus dromedarius). T4 only and T4 and COR levels showed marked seasonal variation with a significant (P<0.05) increase during winter and a significant (P<0.05) decrease during summer. Comparison to summer, MDA levels were significantly (P<0.05) higher in winter, while, CAT activity was significantly lower in winter. A correlation between serum levels of TH and COR, as well as MAD levels and CAT was observed, suggesting that there is an over production of reactive oxygen species (ROS) in camels during winter. The relationships between TH and COR to OS and other circulating hormones, should be identified by further analysis.

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